WeightSnap Tools / Semaglutide reconstitution

Semaglutide Reconstitution Calculator

Enter your semaglutide vial size, how much bacteriostatic water you add, and your dose. Get the concentration, the volume to draw, and the insulin syringe units. Compounded semaglutide vials are commonly 5mg or 10mg. Free, instant, nothing to install.

units
on a U-100 insulin syringe
mL
volume per injection
mg/mL
concentration
doses
per vial at this dose

Semaglutide reconstitution chart

Common semaglutide vial and bacteriostatic water combinations, with the resulting concentration and the U-100 syringe units for reference dose points. Pure arithmetic; your protocol is between you and your provider.

Vial + waterConcentration0.25 mg0.5 mg1 mg1.7 mg2.4 mg
5 mg + 1 mL5 mg/mL510203448
5 mg + 2 mL2.5 mg/mL1020406896
10 mg + 1 mL10 mg/mL2.55101724
10 mg + 2 mL5 mg/mL510203448

Units = (dose ÷ concentration) × 100. A U-100 syringe holds 100 units (1 mL); anything over 100 units will not fit in one syringe.

How the math works

Reconstitution is one division and one multiplication. The water you add sets the concentration, and the concentration turns your dose into a syringe reading.

Concentration = vial (mg) ÷ water (mL)
Volume per injection = dose (mg) ÷ concentration (mg/mL)
Syringe units (U-100) = volume (mL) × 100

Worked example: a 5mg semaglutide vial with 2mL of bacteriostatic water gives 2.5 mg/mL. A 0.5mg dose is 0.5 ÷ 2.5 = 0.2 mL, which reads 20 units on a U-100 syringe. Because semaglutide doses are small, the units are small too, so an accurate syringe matters.

Frequently asked questions

How do you reconstitute semaglutide?

Add bacteriostatic water to the powder vial and let it dissolve gently. The water volume sets the concentration: a 5mg vial with 2mL gives 2.5 mg/mL. Enter your vial and water above to see the units for your dose.

How much bacteriostatic water for a 5mg semaglutide vial?

Any amount works and only changes the concentration. 1mL gives 5 mg/mL and 2mL gives 2.5 mg/mL. Because semaglutide doses are small, more water can make small doses easier to measure accurately on the syringe.

How many units is a semaglutide dose?

Divide your dose in mg by the concentration, then multiply by 100. Example: 0.5mg at 2.5 mg/mL is 0.2 mL, or 20 units. The calculator does this for you.

Does this work for Ozempic or Wegovy pens?

This calculator is for reconstituting powder vials, such as compounded semaglutide. Brand pens (Ozempic, Wegovy) are pre-filled and do not require reconstitution.

Is this medical advice?

No. It converts the numbers you enter into concentration, volume, and units and recommends nothing. Always confirm anything affecting your health with your pharmacist or provider.

This calculator does arithmetic on the numbers you enter. It does not recommend a dose, a schedule, or a product. Semaglutide dosing is titrated by your prescriber; anything affecting your health belongs with your pharmacist or provider.
Mixing new vials often? The WeightSnap app stores your vial and concentration, shows the units for each entry automatically, and tracks how much is left. Need a different tool? Use the general peptide reconstitution calculator for any compound, or the blend calculator for multi-peptide vials. The research hub has real-world data from 14,252 patient reports.

WeightSnap is a tracking tool, not medical advice. This calculator performs arithmetic on the numbers you enter and makes no recommendations. Always work with your healthcare provider.